Hypokalemic Periodic Paralysis

An autosomal dominant familial disorder characterized by recurrent episodes of skeletal muscle weakness associated with falls in serum potassium levels. The condition usually presents in the first or second decade of life with attacks of trunk and leg paresis during sleep or shortly after awakening. Symptoms may persist for hours to days and generally are precipitated by exercise or a meal high in carbohydrates. (Adams et al., Principles of Neurology, 6th ed, p1483)

Also Known As:

Periodic Paralysis, Hypokalemic; HOKPP; HYPOKPP; HYPOPP; Hypokalemic Periodic Paralysis, Familial; Periodic Paralysis- Hypokalemic; Westphall Disease; Periodic Paralysis Hypokalemic; Periodic Paralysis- Hypokalemics; Familial Hypokalemic Periodic Paralysis; Paralysis, Hypokalemic Periodic; Primary Hypokalemic Periodic Paralysis

Musculoskeletal Diseases: 719
- Muscular Diseases: 10128
  - Familial Periodic Paralyses: 71
    - Hypokalemic Periodic Paralysis: 357
Nervous System Diseases: 14178
- Neuromuscular Diseases: 2005
  - Muscular Diseases: 10128
    - Familial Periodic Paralyses: 71
      - Hypokalemic Periodic Paralysis: 357
Congenital, Hereditary, and Neonatal Diseases and Abnormalities: 933
- Inborn Genetic Diseases: 11939
  - Inborn Errors Metabolism: 1162
    - Inborn Errors Metal Metabolism
      - Familial Periodic Paralyses: 71
        Hypokalemic Periodic Paralysis: 357
Nutritional and Metabolic Diseases: 15
- Metabolic Diseases: 10142
  - Inborn Errors Metabolism: 1162
    - Inborn Errors Metal Metabolism
      - Familial Periodic Paralyses: 71
        Hypokalemic Periodic Paralysis: 357

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